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(S)-1-[3,5-Bis­(trifluoro­meth­yl)phen­yl]-N-methylethyl­amine–(R)-2-hydroxy­butane­dioic acid (1/1)

In the title compound, C(11)H(11)F(6)N·C(4)H(6)O(5), a key inter­mediate in the synthesis of the NK1 receptor antagonist of casopitant, the F atoms of the trifluoro­methyl groups are disordered over two sites with equal occupancies. In the crystal, the components are linked by bifurcated N—H⋯(O,O) h...

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Detalles Bibliográficos
Autores principales: Zhu, Hai-Bin, Ji, Jun-Feng, Wang, Hai
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968104/
https://www.ncbi.nlm.nih.gov/pubmed/21581651
http://dx.doi.org/10.1107/S1600536808043201