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WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

The WRAP53 gene gives rise to a p53 antisense transcript that regulates p53. This gene also encodes a protein that directs small Cajal body–specific RNAs to Cajal bodies. Cajal bodies are nuclear organelles involved in diverse functions such as processing ribonucleoproteins important for splicing. H...

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Detalles Bibliográficos
Autores principales: Mahmoudi, Salah, Henriksson, Sofia, Weibrecht, Irene, Smith, Stephen, Söderberg, Ola, Strömblad, Staffan, Wiman, Klas G., Farnebo, Marianne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970535/
https://www.ncbi.nlm.nih.gov/pubmed/21072240
http://dx.doi.org/10.1371/journal.pbio.1000521