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Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

BACKGROUND: Expansion of the CGG trinucleotide repeat in the 5′-untranslated region of the FMR1, fragile X mental retardation 1, gene results in suppression of protein expression for this gene and is the underlying cause of Fragile X syndrome. In unaffected individuals, the FMRP protein, together wi...

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Detalles Bibliográficos
Autores principales: Adams-Cioaba, Melanie A., Guo, Yahong, Bian, ChuanBing, Amaya, Maria F., Lam, Robert, Wasney, Gregory A., Vedadi, Masoud, Xu, Chao, Min, Jinrong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970552/
https://www.ncbi.nlm.nih.gov/pubmed/21072162
http://dx.doi.org/10.1371/journal.pone.0013559