p21-Activated Kinases Are Required for Transformation in a Cell-Based Model of Neurofibromatosis Type 2

BACKGROUND: NF2 is an autosomal dominant disease characterized by development of bilateral vestibular schwannomas and other benign tumors in central nervous system. Loss of the NF2 gene product, Merlin, leads to aberrant Schwann cell proliferation, motility, and survival, but the mechanisms by which...

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Detalles Bibliográficos
Autores principales: Chow, Hoi Yee, Stepanova, Dina, Koch, Jennifer, Chernoff, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970553/
https://www.ncbi.nlm.nih.gov/pubmed/21072183
http://dx.doi.org/10.1371/journal.pone.0013791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970553/
https://www.ncbi.nlm.nih.gov/pubmed/21072183
http://dx.doi.org/10.1371/journal.pone.0013791

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