Cargando…

p21-Activated Kinases Are Required for Transformation in a Cell-Based Model of Neurofibromatosis Type 2

BACKGROUND: NF2 is an autosomal dominant disease characterized by development of bilateral vestibular schwannomas and other benign tumors in central nervous system. Loss of the NF2 gene product, Merlin, leads to aberrant Schwann cell proliferation, motility, and survival, but the mechanisms by which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chow, Hoi Yee, Stepanova, Dina, Koch, Jennifer, Chernoff, Jonathan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970553/ https://www.ncbi.nlm.nih.gov/pubmed/21072183 http://dx.doi.org/10.1371/journal.pone.0013791

Ejemplares similares

Targeting Group I p21-Activated Kinases to Control Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis
por: Semenova, Galina, et al.
Publicado: (2017)

p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts
por: Sells, Mary Ann, et al.
Publicado: (1999)

Targeting P21-Activated Kinase-1 for Metastatic Prostate Cancer
por: Somanath, Payaningal R., et al.
Publicado: (2023)

The role of p21-activated kinase in the initiation of atherosclerosis
por: Jhaveri, K A, et al.
Publicado: (2012)

A new concept in NF2 pharmacotherapy: targeting fatty acid synthesis
por: Stepanova, Dina S., et al.
Publicado: (2018)

Effects of p21-activated kinase 1 inhibition on 11q13 amplified ovarian cancer cells
por: Prudnikova, Tatiana Y., et al.
Publicado: (2015)

NFB-21. Neurofibromatosis Type I in the Setting of Neuro-Oncology
por: Hemenway, Molly
Publicado: (2022)

Inhibition of p21 Activated Kinase (PAK) Reduces Airway Responsiveness In Vivo and In Vitro in Murine and Human Airways
por: Hoover, Wyn C., et al.
Publicado: (2012)

Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice
por: Singh, Nikhlesh K., et al.
Publicado: (2015)

p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils
por: Itakura, Asako, et al.
Publicado: (2013)

Targeting LIM kinase in cancer and neurofibromatosis
por: Rak, Roni, et al.
Publicado: (2014)

LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2
por: Petrilli, Alejandra, et al.
Publicado: (2013)

A p21-Activated Kinase Is Required for Conidial Germination in Penicillium marneffei
por: Boyce, Kylie J, et al.
Publicado: (2007)

Seizures in children with neurofibromatosis type 1: is neurofibromatosis type 1 enough?
por: Santoro, Claudia, et al.
Publicado: (2018)

Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer
por: Korobeynikov, Vladislav, et al.
Publicado: (2019)

Dermatologic Manifestations of Neurofibromatosis Type 1 and Emerging Treatments
por: Poplausky, Dina, et al.
Publicado: (2023)

Regulation of Mixed Lineage Kinase 3 is Required for Neurofibromatosis-2-Mediated Growth Suppression in Human Cancer
por: Zhan, Yu, et al.
Publicado: (2010)

Neurofibromatosis type 1
por: Mançano, Alexandre Dias
Publicado: (2022)

Neurofibromatosis type 1 and pregnancy: The transformation of a nodular to cystic neurofibroma in the cervical region
por: Ramos-Zúñiga, Rodrigo, et al.
Publicado: (2015)

Requirement of p21-activated Kinase (PAK) for Salmonella typhimurium–induced Nuclear Responses
por: Chen, Li-Mei, et al.
Publicado: (1999)

Zebrafish model of neurofibromatosis type 1
Publicado: (2012)

Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2)
por: Shen, Yu-chi, et al.
Publicado: (2019)

Cranio-orbital-temporal neurofibromatosis: An uncommon subtype of neurofibromatosis type-1
por: Acharya, Nibedita, et al.
Publicado: (2014)

Sensory Processing in Children and Adolescents with Neurofibromatosis Type 1
por: Pride, Natalie A., et al.
Publicado: (2023)

Plexiform neurofibromatosis type 1
por: Sharma, Surendra K., et al.
Publicado: (2016)

Neurofibromatosis Type 1 in the Mandible
por: Uchiyama, Yuka, et al.
Publicado: (2018)

Hemostasis and Type 1 Neurofibromatosis
por: Niddam, Jeremy, et al.
Publicado: (2017)

Plexiform neurofibroma of the liver, with malignant transformation to MPNST, in a pediatric patient without neurofibromatosis type 1
por: Ioannou, Maria, et al.
Publicado: (2023)

The p21-Activated Kinase (PAK) Family Member PakD Is Required for Chemorepulsion and Proliferation Inhibition by Autocrine Signals in Dictyostelium discoideum
por: Phillips, Jonathan E., et al.
Publicado: (2014)

p21-Activated Kinase 1 Promotes Breast Tumorigenesis via Phosphorylation and Activation of the Calcium/Calmodulin-Dependent Protein Kinase II
por: Saldivar-Cerón, Héctor I., et al.
Publicado: (2022)

Statins, bone, and neurofibromatosis type 1
por: Korf, Bruce R
Publicado: (2008)

Moyamoya syndrome and neurofibromatosis type 1
por: Vargiami, Euthymia, et al.
Publicado: (2014)

Neurofibromatosis Type 1 with Bladder Involvement
por: Üre, Iyimser, et al.
Publicado: (2013)

Becker's nevus with neurofibromatosis type 1
por: Kar, Sumit, et al.
Publicado: (2015)

Meningioangiomatosis Without Neurofibromatosis Type 2
por: Marzi, Sara, et al.
Publicado: (2012)

Constipation in adults with neurofibromatosis type 1
por: Ejerskov, Cecilie, et al.
Publicado: (2017)

Brain tumors in neurofibromatosis type 1
por: Costa, Amanda De Andrade, et al.
Publicado: (2019)

Cutaneous Findings in Neurofibromatosis Type 1
por: Ozarslan, Bengisu, et al.
Publicado: (2021)

Bone Manifestations of Neurofibromatosis Type 1
por: Diallo, Ibrahima Dokal, et al.
Publicado: (2022)

Psychiatric symptoms in neurofibromatosis type 2
por: Khouadja, S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o21r806hu654m112joktj3m70e