Human functional genetic studies are biased against the medically most relevant primate-specific genes

BACKGROUND: Many functional, structural and evolutionary features of human genes have been observed to correlate with expression breadth and/or gene age. Here, we systematically explore these correlations. RESULTS: Gene age and expression breadth are strongly correlated, but contribute independently...

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Detalles Bibliográficos
Autores principales: Hao, Lili, Ge, Xiaomeng, Wan, Haolei, Hu, Songnian, Lercher, Martin J, Yu, Jun, Chen, Wei-Hua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970608/
https://www.ncbi.nlm.nih.gov/pubmed/20961448
http://dx.doi.org/10.1186/1471-2148-10-316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970608/
https://www.ncbi.nlm.nih.gov/pubmed/20961448
http://dx.doi.org/10.1186/1471-2148-10-316

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