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Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are common mesenchymal neoplasms in the gastrointestinal tract of humans and dogs. Little is known about the pathogenesis of these tumors. This study evaluated the role of c-KIT in canine GISTs; specifically, we investigated activating mutations in...

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Detalles Bibliográficos
Autores principales: Gregory-Bryson, Emmalena, Bartlett, Elizabeth, Kiupel, Matti, Hayes, Schantel, Yuzbasiyan-Gurkan, Vilma
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970610/
https://www.ncbi.nlm.nih.gov/pubmed/20950418
http://dx.doi.org/10.1186/1471-2407-10-559