Protease-activated receptor-2 mediates the expression of inflammatory cytokines, antimicrobial peptides, and matrix metalloproteinases in keratinocytes in response to Propionibacterium acnes

Propionibacterium acnes (P. acnes) has been known to produce various exogenous proteases, however, their role in acne pathogenesis remains largely unknown. Proteases elicit cellular responses, at least in part, via proteinase-activated receptor-2 (PAR-2), which is known to mediate inflammation and i...

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Detalles Bibliográficos
Autores principales: Lee, Sang Eun, Kim, Ji-Min, Jeong, Se Kyoo, Jeon, Jeong Eun, Yoon, Hyun-Ju, Jeong, Min-Kyung, Lee, Seung Hun
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970807/
https://www.ncbi.nlm.nih.gov/pubmed/20697725
http://dx.doi.org/10.1007/s00403-010-1074-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970807/
https://www.ncbi.nlm.nih.gov/pubmed/20697725
http://dx.doi.org/10.1007/s00403-010-1074-z

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