SeqEM: an adaptive genotype-calling approach for next-generation sequencing studies

Motivation: Next-generation sequencing presents several statistical challenges, with one of the most fundamental being determining an individual's genotype from multiple aligned short read sequences at a position. Some simple approaches for genotype calling apply fixed filters, such as calling...

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Detalles Bibliográficos
Autores principales: Martin, E. R., Kinnamon, D. D., Schmidt, M. A., Powell, E. H., Zuchner, S., Morris, R. W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971572/
https://www.ncbi.nlm.nih.gov/pubmed/20861027
http://dx.doi.org/10.1093/bioinformatics/btq526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971572/
https://www.ncbi.nlm.nih.gov/pubmed/20861027
http://dx.doi.org/10.1093/bioinformatics/btq526

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