(S)-6-Chloro-4-cyclo­propyl­ethynyl-4-trifluoro­methyl-1H-3,1-benzoxazin-2(4H)-one

Two independent mol­ecules comprise the crystallographic asymmetric unit in the title anti­retroviral agent Efavirenz, C(14)H(9)ClF(3)NO(2), and these have noteworthy differences in conformation. The major difference relates to the orientation of the 2-cyclo­propyl­ethynyl residue relative to the si...

Descripción completa

Detalles Bibliográficos
Autores principales: Cuffini, Silvia, Howie, R. Alan, Tiekink, Edward R. T., Wardell, James L., Wardell, Solange M. S. V.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971961/
https://www.ncbi.nlm.nih.gov/pubmed/21578886
http://dx.doi.org/10.1107/S1600536809049101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2971961/
https://www.ncbi.nlm.nih.gov/pubmed/21578886
http://dx.doi.org/10.1107/S1600536809049101

Ejemplares similares