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1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxyquinolin-4-yl)methyl]thiourea–l-proline–methanol (1/1/1)
In the methanol solvate of the title 1:1 cocrystal, C(29)H(28)F(6)N(4)OS·C(5)H(9)NO(2)·CH(4)O, the l-proline molecule exists as a zwitterion. In the crystal, the disubstituted thiourea, l-proline and methanol molecules are linked by N—H⋯O and N—H⋯N hydrogen bonds, forming a two-dimensional array...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972067/ https://www.ncbi.nlm.nih.gov/pubmed/21578800 http://dx.doi.org/10.1107/S1600536809047072 |