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1-[3,5-Bis(trifluoro­meth­yl)phen­yl]-3-[(5-ethenyl-1-aza­bicyclo­[2.2.2]octan-2-yl)(6-methoxy­quinolin-4-yl)meth­yl]thio­urea–l-proline–methanol (1/1/1)

In the methanol solvate of the title 1:1 cocrystal, C(29)H(28)F(6)N(4)OS·C(5)H(9)NO(2)·CH(4)O, the l-proline mol­ecule exists as a zwitterion. In the crystal, the disubstituted thio­urea, l-proline and methanol mol­ecules are linked by N—H⋯O and N—H⋯N hydrogen bonds, forming a two-dimensional array...

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Detalles Bibliográficos
Autores principales: Muramulla, Savitha, Arman, Hadi D., Zhao, Cong-Gui, Tiekink, Edward R. T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972067/
https://www.ncbi.nlm.nih.gov/pubmed/21578800
http://dx.doi.org/10.1107/S1600536809047072