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1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)(6-methoxyquinolin-4-yl)methyl]thiourea–l-proline–methanol (1/1/1)

In the methanol solvate of the title 1:1 cocrystal, C(29)H(28)F(6)N(4)OS·C(5)H(9)NO(2)·CH(4)O, the l-proline molecule exists as a zwitterion. In the crystal, the disubstituted thiourea, l-proline and methanol molecules are linked by N—H⋯O and N—H⋯N hydrogen bonds, forming a two-dimensional array...

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Detalles Bibliográficos
Autores principales:	Muramulla, Savitha, Arman, Hadi D., Zhao, Cong-Gui, Tiekink, Edward R. T.
Formato:	Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2009
Materias:	Organic Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972067/ https://www.ncbi.nlm.nih.gov/pubmed/21578800 http://dx.doi.org/10.1107/S1600536809047072

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