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Regulation and Cytoprotective Role of Hexokinase III

BACKGROUND: Hexokinases (HKs) catalyze the first step in glucose metabolism. Of the three mammalian 100-kDa HK isoforms, HKI and II can bind to mitochondria and protect against cell death. HKIII does not bind mitochondria, and little is known about its regulation or cytoprotective effects. We studie...

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Detalles Bibliográficos
Autores principales: Wyatt, Eugene, Wu, Rongxue, Rabeh, Wael, Park, Hee-Won, Ghanefar, Mohsen, Ardehali, Hossein
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972215/
https://www.ncbi.nlm.nih.gov/pubmed/21072205
http://dx.doi.org/10.1371/journal.pone.0013823