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Regulation and Cytoprotective Role of Hexokinase III
BACKGROUND: Hexokinases (HKs) catalyze the first step in glucose metabolism. Of the three mammalian 100-kDa HK isoforms, HKI and II can bind to mitochondria and protect against cell death. HKIII does not bind mitochondria, and little is known about its regulation or cytoprotective effects. We studie...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972215/ https://www.ncbi.nlm.nih.gov/pubmed/21072205 http://dx.doi.org/10.1371/journal.pone.0013823 |