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Breast Cancer Stem-Like Cells Are Inhibited by a Non-Toxic Aryl Hydrocarbon Receptor Agonist

BACKGROUND: Cancer stem cells (CSCs) have increased resistance to cancer chemotherapy. They can be enriched as drug-surviving CSCs (D-CSCs) by growth with chemotherapeutic drugs, and/or by sorting of cells expressing CSC markers such as aldehyde dehydrogenase-1 (ALDH). CSCs form colonies in agar, ma...

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Detalles Bibliográficos
Autores principales: Prud'homme, Gérald J., Glinka, Yelena, Toulina, Anna, Ace, Olga, Subramaniam, Venkateswaran, Jothy, Serge
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972222/
https://www.ncbi.nlm.nih.gov/pubmed/21072210
http://dx.doi.org/10.1371/journal.pone.0013831