RBP-J is not required for granule neuron progenitor development and medulloblastoma initiated by Hedgehog pathway activation in the external germinal layer

BACKGROUND: The Notch signalling pathway plays crucial roles in neural development, functioning by preventing premature differentiation and promotion of glial cell fates. In the developing cerebellum Notch pathway components are expressed in granule neuron progenitors of the external germinal layer...

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Detalles Bibliográficos
Autores principales: Julian, Elaine, Hallahan, Andrew R, Wainwright, Brandon J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972267/
https://www.ncbi.nlm.nih.gov/pubmed/20950430
http://dx.doi.org/10.1186/1749-8104-5-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972267/
https://www.ncbi.nlm.nih.gov/pubmed/20950430
http://dx.doi.org/10.1186/1749-8104-5-27

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