Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon α

It has been reported that hepatitis B virus (HBV) core protein (HBc) can inhibit the transcription of human interferon-induced MxA gene. In this study, we investigated whether HBc protein mutations at hot spots (L60V, S87G and I97L) could still inhibit MxA transcription and the potential significanc...

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Detalles Bibliográficos
Autores principales: Zhijian, Yu, Zhen, Huang, Fan, Zhang, Jin, Yang, Qiwen, Deng, Zhongming, Zeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972278/
https://www.ncbi.nlm.nih.gov/pubmed/20959021
http://dx.doi.org/10.1186/1743-422X-7-278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972278/
https://www.ncbi.nlm.nih.gov/pubmed/20959021
http://dx.doi.org/10.1186/1743-422X-7-278

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