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GAPDH Mediates Nitrosylation of Nuclear Proteins

S-nitrosylation by nitric oxide (NO) is a major mode of signaling to cellular proteins1, including prominent nuclear proteins such as HDAC22 and PARP13. The high reactivity of the NO group with protein thiols implies the existence of selective targeting mechanisms. Specificity of NO signaling is oft...

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Detalles Bibliográficos
Autores principales: Kornberg, Michael D., Sen, Nilkantha, Hara, Makoto R., Juluri, Krishna R., Van K. Nguyen, Judy, Snowman, Adele M., Law, Lindsey, Hester, Lynda D., Snyder, Solomon H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972384/
https://www.ncbi.nlm.nih.gov/pubmed/20972425
http://dx.doi.org/10.1038/ncb2114