Ascl1a regulates Müller glia dedifferentiation and retina regeneration via a Lin-28-dependent, let-7 miRNA signaling pathway

Unlike mammals, teleost fish mount a robust regenerative response to retinal injury that culminates in restoration of visual function1, 2. This regenerative response relies on Müller glia (MG) dedifferentiation into a cycling population of progenitor cells. However, the mechanism underlying this ded...

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Detalles Bibliográficos
Autores principales: Ramachandran, Rajesh, Fausett, Blake V., Goldman, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972404/
https://www.ncbi.nlm.nih.gov/pubmed/20935637
http://dx.doi.org/10.1038/ncb2115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972404/
https://www.ncbi.nlm.nih.gov/pubmed/20935637
http://dx.doi.org/10.1038/ncb2115

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