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The Effect of Tribbles-Related Protein 3 on ER Stress-Suppressed Insulin Gene Expression in INS-1 Cells

BACKGROUND: The highly developed endoplasmic reticulum (ER) structure in pancreatic beta cells is heavily involved in insulin biosynthesis. Thus, any perturbation in ER function inevitably impacts insulin biosynthesis. Recent studies showed that the expression of tribbles-related protein 3 (TRB3), a...

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Detalles Bibliográficos
Autores principales: Jang, Young Yun, Kim, Nam Keong, Kim, Mi Kyung, Lee, Ho Young, Kim, Sang Jin, Kim, Hye Soon, Seo, Hye-Young, Lee, In Kyu, Park, Keun Gyu
Formato: Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972491/
https://www.ncbi.nlm.nih.gov/pubmed/21076579
http://dx.doi.org/10.4093/kdj.2010.34.5.312