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The Effect of Tribbles-Related Protein 3 on ER Stress-Suppressed Insulin Gene Expression in INS-1 Cells
BACKGROUND: The highly developed endoplasmic reticulum (ER) structure in pancreatic beta cells is heavily involved in insulin biosynthesis. Thus, any perturbation in ER function inevitably impacts insulin biosynthesis. Recent studies showed that the expression of tribbles-related protein 3 (TRB3), a...
Autores principales: | Jang, Young Yun, Kim, Nam Keong, Kim, Mi Kyung, Lee, Ho Young, Kim, Sang Jin, Kim, Hye Soon, Seo, Hye-Young, Lee, In Kyu, Park, Keun Gyu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972491/ https://www.ncbi.nlm.nih.gov/pubmed/21076579 http://dx.doi.org/10.4093/kdj.2010.34.5.312 |
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