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Structural interpretation of P2X receptor mutagenesis studies on drug action
P2X receptors for ATP are ligand gated cation channels that form from the trimeric assembly of subunits with two transmembrane segments, a large extracellular ligand binding loop, and intracellular amino and carboxy termini. The receptors are expressed throughout the body, involved in functions rang...
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Formato: | Texto |
Lenguaje: | English |
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Blackwell Publishing Ltd
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972645/ https://www.ncbi.nlm.nih.gov/pubmed/20977449 http://dx.doi.org/10.1111/j.1476-5381.2010.00728.x |