Generation of Humoral Immune Responses to Multi-Allele PfAMA1 Vaccines; Effect of Adjuvant and Number of Component Alleles on the Breadth of Response

There is increasing interest in multi-allele vaccines to overcome strain-specificity against polymorphic vaccine targets such as Apical Membrane Antigen 1 (AMA1). These have been shown to induce broad inhibitory antibodies in vitro and formed the basis for the design of three Diversity-Covering (DiC...

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Detalles Bibliográficos
Autores principales: Kusi, Kwadwo A., Faber, Bart W., Riasat, Vanessa, Thomas, Alan W., Kocken, Clemens H. M., Remarque, Edmond J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972715/
https://www.ncbi.nlm.nih.gov/pubmed/21082025
http://dx.doi.org/10.1371/journal.pone.0015391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972715/
https://www.ncbi.nlm.nih.gov/pubmed/21082025
http://dx.doi.org/10.1371/journal.pone.0015391

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