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Monte Carlo Analysis of Neck Linker Extension in Kinesin Molecular Motors

Kinesin stepping is thought to involve both concerted conformational changes and diffusive movement, but the relative roles played by these two processes are not clear. The neck linker docking model is widely accepted in the field, but the remainder of the step – diffusion of the tethered head to th...

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Detalles Bibliográficos
Autores principales: Kutys, Matthew L., Fricks, John, Hancock, William O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973807/
https://www.ncbi.nlm.nih.gov/pubmed/21079666
http://dx.doi.org/10.1371/journal.pcbi.1000980