The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications

We report a computational approach that integrates structural bioinformatics, molecular modelling and systems biology to construct a drug-target network on a structural proteome-wide scale. The approach has been applied to the genome of Mycobacterium tuberculosis (M.tb), the causative agent of one o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinnings, Sarah L., Xie, Li, Fung, Kingston H., Jackson, Richard M., Xie, Lei, Bourne, Philip E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973814/
https://www.ncbi.nlm.nih.gov/pubmed/21079673
http://dx.doi.org/10.1371/journal.pcbi.1000976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973814/
https://www.ncbi.nlm.nih.gov/pubmed/21079673
http://dx.doi.org/10.1371/journal.pcbi.1000976

Ejemplares similares