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The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications
We report a computational approach that integrates structural bioinformatics, molecular modelling and systems biology to construct a drug-target network on a structural proteome-wide scale. The approach has been applied to the genome of Mycobacterium tuberculosis (M.tb), the causative agent of one o...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973814/ https://www.ncbi.nlm.nih.gov/pubmed/21079673 http://dx.doi.org/10.1371/journal.pcbi.1000976 |