Human-Specific Evolution and Adaptation Led to Major Qualitative Differences in the Variable Receptors of Human and Chimpanzee Natural Killer Cells

Natural killer (NK) cells serve essential functions in immunity and reproduction. Diversifying these functions within individuals and populations are rapidly-evolving interactions between highly polymorphic major histocompatibility complex (MHC) class I ligands and variable NK cell receptors. Specif...

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Detalles Bibliográficos
Autores principales: Abi-Rached, Laurent, Moesta, Achim K., Rajalingam, Raja, Guethlein, Lisbeth A., Parham, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973822/
https://www.ncbi.nlm.nih.gov/pubmed/21079681
http://dx.doi.org/10.1371/journal.pgen.1001192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973822/
https://www.ncbi.nlm.nih.gov/pubmed/21079681
http://dx.doi.org/10.1371/journal.pgen.1001192

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