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Human-Specific Evolution and Adaptation Led to Major Qualitative Differences in the Variable Receptors of Human and Chimpanzee Natural Killer Cells
Natural killer (NK) cells serve essential functions in immunity and reproduction. Diversifying these functions within individuals and populations are rapidly-evolving interactions between highly polymorphic major histocompatibility complex (MHC) class I ligands and variable NK cell receptors. Specif...
Autores principales: | Abi-Rached, Laurent, Moesta, Achim K., Rajalingam, Raja, Guethlein, Lisbeth A., Parham, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973822/ https://www.ncbi.nlm.nih.gov/pubmed/21079681 http://dx.doi.org/10.1371/journal.pgen.1001192 |
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