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ATM Limits Incorrect End Utilization during Non-Homologous End Joining of Multiple Chromosome Breaks
Chromosome rearrangements can form when incorrect ends are matched during end joining (EJ) repair of multiple chromosomal double-strand breaks (DSBs). We tested whether the ATM kinase limits chromosome rearrangements via suppressing incorrect end utilization during EJ repair of multiple DSBs. For th...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973825/ https://www.ncbi.nlm.nih.gov/pubmed/21079684 http://dx.doi.org/10.1371/journal.pgen.1001194 |