ATM Limits Incorrect End Utilization during Non-Homologous End Joining of Multiple Chromosome Breaks

Chromosome rearrangements can form when incorrect ends are matched during end joining (EJ) repair of multiple chromosomal double-strand breaks (DSBs). We tested whether the ATM kinase limits chromosome rearrangements via suppressing incorrect end utilization during EJ repair of multiple DSBs. For th...

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Detalles Bibliográficos
Autores principales: Bennardo, Nicole, Stark, Jeremy M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973825/
https://www.ncbi.nlm.nih.gov/pubmed/21079684
http://dx.doi.org/10.1371/journal.pgen.1001194

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