Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epithelial cells. TLR3 was constitutively expressed; h...

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Detalles Bibliográficos
Autores principales: Slater, Louise, Bartlett, Nathan W., Haas, Jennifer J., Zhu, Jie, Message, Simon D., Walton, Ross P., Sykes, Annemarie, Dahdaleh, Samer, Clarke, Deborah L., Belvisi, Maria G., Kon, Onn M., Fujita, Takashi, Jeffery, Peter K., Johnston, Sebastian L., Edwards, Michael R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973831/
https://www.ncbi.nlm.nih.gov/pubmed/21079690
http://dx.doi.org/10.1371/journal.ppat.1001178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973831/
https://www.ncbi.nlm.nih.gov/pubmed/21079690
http://dx.doi.org/10.1371/journal.ppat.1001178

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