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Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epithelial cells. TLR3 was constitutively expressed; h...
Autores principales: | Slater, Louise, Bartlett, Nathan W., Haas, Jennifer J., Zhu, Jie, Message, Simon D., Walton, Ross P., Sykes, Annemarie, Dahdaleh, Samer, Clarke, Deborah L., Belvisi, Maria G., Kon, Onn M., Fujita, Takashi, Jeffery, Peter K., Johnston, Sebastian L., Edwards, Michael R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973831/ https://www.ncbi.nlm.nih.gov/pubmed/21079690 http://dx.doi.org/10.1371/journal.ppat.1001178 |
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