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Antioxidants Protect Keratinocytes against M. ulcerans Mycolactone Cytotoxicity
BACKGROUND: Mycobacterium ulcerans is the causative agent of necrotizing skin ulcerations in distinctive geographical areas. M. ulcerans produces a macrolide toxin, mycolactone, which has been identified as an important virulence factor in ulcer formation. Mycolactone is cytotoxic to fibroblasts and...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973957/ https://www.ncbi.nlm.nih.gov/pubmed/21079804 http://dx.doi.org/10.1371/journal.pone.0013839 |