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Antioxidants Protect Keratinocytes against M. ulcerans Mycolactone Cytotoxicity

BACKGROUND: Mycobacterium ulcerans is the causative agent of necrotizing skin ulcerations in distinctive geographical areas. M. ulcerans produces a macrolide toxin, mycolactone, which has been identified as an important virulence factor in ulcer formation. Mycolactone is cytotoxic to fibroblasts and...

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Detalles Bibliográficos
Autores principales:	Grönberg, Alvar, Zettergren, Louise, Bergh, Kerstin, Ståhle, Mona, Heilborn, Johan, Ängeby, Kristian, Small, Pamela L., Akuffo, Hannah, Britton, Sven
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973957/ https://www.ncbi.nlm.nih.gov/pubmed/21079804 http://dx.doi.org/10.1371/journal.pone.0013839

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