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Changes to Euchromatin on LAT and ICP4 Following Reactivation Are More Prevalent in an Efficiently Reactivating Strain of HSV-1

BACKGROUND: Epigenetic mechanisms, via post-translational histone modifications, have roles in the establishment and maintenance of latency of the HSV-1 genome in the sensory neurons. Considering that many post-translational histone marks are reversible in nature, epigenetic mechanisms may also play...

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Detalles Bibliográficos
Autores principales: Creech, Clinton C., Neumann, Donna M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973973/
https://www.ncbi.nlm.nih.gov/pubmed/21079815
http://dx.doi.org/10.1371/journal.pone.0015416