Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution

[Image: see text] The partial unfolding of human lysozyme underlies its conversion from the soluble state into amyloid fibrils observed in a fatal hereditary form of systemic amyloidosis. To understand the molecular origins of the disease, it is critical to characterize the structural and physicoche...

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Detalles Bibliográficos
Autores principales: Dhulesia, Anne, Cremades, Nunilo, Kumita, Janet R., Hsu, Shang-Te Danny, Mossuto, Maria F., Dumoulin, Mireille, Nietlispach, Daniel, Akke, Mikael, Salvatella, Xavier, Dobson, Christopher M.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974344/
https://www.ncbi.nlm.nih.gov/pubmed/20958028
http://dx.doi.org/10.1021/ja103524m

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974344/
https://www.ncbi.nlm.nih.gov/pubmed/20958028
http://dx.doi.org/10.1021/ja103524m

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