Cargando…
Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution
[Image: see text] The partial unfolding of human lysozyme underlies its conversion from the soluble state into amyloid fibrils observed in a fatal hereditary form of systemic amyloidosis. To understand the molecular origins of the disease, it is critical to characterize the structural and physicoche...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2010
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974344/ https://www.ncbi.nlm.nih.gov/pubmed/20958028 http://dx.doi.org/10.1021/ja103524m |