Interaction-Dependent PCR: Identification of Ligand−Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment

[Image: see text] Interaction-dependent PCR (IDPCR) is a solution-phase method to identify binding partners from combined libraries of small-molecule ligands and targets in a single experiment. Binding between DNA-linked targets and DNA-linked ligands induces formation of an extendable duplex. Exten...

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Detalles Bibliográficos
Autores principales: McGregor, Lynn M., Gorin, David J., Dumelin, Christoph E., Liu, David R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974369/
https://www.ncbi.nlm.nih.gov/pubmed/20949943
http://dx.doi.org/10.1021/ja107677q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974369/
https://www.ncbi.nlm.nih.gov/pubmed/20949943
http://dx.doi.org/10.1021/ja107677q

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