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Phase I Study of Safety and Immunogenicity of an Escherichia coli-Derived Recombinant Protective Antigen (rPA) Vaccine to Prevent Anthrax in Adults

BACKGROUND: The fatal disease caused by Bacillus anthracis is preventable with a prophylactic vaccine. The currently available anthrax vaccine requires a lengthy immunization schedule, and simpler and more immunogenic options for protection against anthrax are a priority for development. In this rep...

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Detalles Bibliográficos
Autores principales: Brown, Bruce K., Cox, Josephine, Gillis, Anita, VanCott, Thomas C., Marovich, Mary, Milazzo, Mark, Antonille, Tanya Santelli, Wieczorek, Lindsay, McKee, Kelly T., Metcalfe, Karen, Mallory, Raburn M., Birx, Deborah, Polonis, Victoria R., Robb, Merlin L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974626/
https://www.ncbi.nlm.nih.gov/pubmed/21079762
http://dx.doi.org/10.1371/journal.pone.0013849