Defects in Innate Immunity Render Breast Cancer Initiating Cells Permissive to Oncolytic Adenovirus

BACKGROUND: Cancer stem cells/initiating cells (CSC/CIC), are thought to exist as a small population in malignant tissues. They are resistant to conventional cancer treatments and possibly underlie post-treatment relapse. The CIC population can be targeted with capsid modified oncolytic adenoviruses...

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Detalles Bibliográficos
Autores principales: Ahtiainen, Laura, Mirantes, Cristina, Jahkola, Tiina, Escutenaire, Sophie, Diaconu, Iulia, Österlund, Pamela, Kanerva, Anna, Cerullo, Vincenzo, Hemminki, Akseli
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974645/
https://www.ncbi.nlm.nih.gov/pubmed/21079774
http://dx.doi.org/10.1371/journal.pone.0013859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974645/
https://www.ncbi.nlm.nih.gov/pubmed/21079774
http://dx.doi.org/10.1371/journal.pone.0013859

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