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Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation
BACKGROUND: Neuropilin is a transmembrane receptor for vascular endothelial growth factor (VEGF) and is expressed in normal endothelial cells and upregulated in cancer cells. Neuropilin-1 (NRP-1) has been shown to promote tumour cell migration and survival in colon cancer in response to VEGF binding...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974727/ https://www.ncbi.nlm.nih.gov/pubmed/20950431 http://dx.doi.org/10.1186/1476-4598-9-276 |