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Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca(2+ )permeability and Mg(2+ )block

BACKGROUND: Members of the complex N-methyl-D-aspartate receptor (NMDAR) subfamily of ionotropic glutamate receptors (iGluRs) conventionally assemble from NR1 and NR2 subunits, the composition of which determines receptor properties. Hallmark features of conventional NMDARs include the requirement f...

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Detalles Bibliográficos
Autores principales: Cavara, Nora A, Orth, Angela, Hicking, Gordon, Seebohm, Guiscard, Hollmann, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974739/
https://www.ncbi.nlm.nih.gov/pubmed/20958962
http://dx.doi.org/10.1186/1471-2202-11-133