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mRNA expression analysis of cell cycle genes in islets of pregnant mice

AIMS/HYPOTHESIS: Pregnancy requires an increase in the functional beta cell mass to match metabolic needs for insulin. To understand this adaptation at the molecular level, we undertook a time course analysis of mRNA expression in mice. METHODS: Total RNA extracted from C57Bl6/J mouse islets every 3...

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Detalles Bibliográficos
Autores principales: Schraenen, A., de Faudeur, G., Thorrez, L., Lemaire, K., Van Wichelen, G., Granvik, M., Van Lommel, L., in’t Veld, P., Schuit, F.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974927/
https://www.ncbi.nlm.nih.gov/pubmed/20886204
http://dx.doi.org/10.1007/s00125-010-1912-8