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mRNA expression analysis of cell cycle genes in islets of pregnant mice
AIMS/HYPOTHESIS: Pregnancy requires an increase in the functional beta cell mass to match metabolic needs for insulin. To understand this adaptation at the molecular level, we undertook a time course analysis of mRNA expression in mice. METHODS: Total RNA extracted from C57Bl6/J mouse islets every 3...
Autores principales: | Schraenen, A., de Faudeur, G., Thorrez, L., Lemaire, K., Van Wichelen, G., Granvik, M., Van Lommel, L., in’t Veld, P., Schuit, F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974927/ https://www.ncbi.nlm.nih.gov/pubmed/20886204 http://dx.doi.org/10.1007/s00125-010-1912-8 |
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