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T cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells

It is well established that full activation of T cells requires the interaction of the TCR complex with the peptide–MHC complex (Signal 1) and additional signals (Signal 2). These second signals are generated by the interaction of costimulatory ligands expressed on antigen presenting cells with acti...

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Detalles Bibliográficos
Autores principales: Leitner, Judith, Kuschei, Werner, Grabmeier-Pfistershammer, Katharina, Woitek, Ramona, Kriehuber, Ernst, Majdic, Otto, Zlabinger, Gerhard, Pickl, Winfried F., Steinberger, Peter
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975062/
https://www.ncbi.nlm.nih.gov/pubmed/20858499
http://dx.doi.org/10.1016/j.jim.2010.09.020