Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization

Ras and Rho small GTPases possessing a C-terminal polybasic region (PBR) are vital signaling proteins whose misregulation can lead to cancer. Signaling by these proteins depends on their ability to bind guanine nucleotides and their prenylation with a geranylgeranyl or farnesyl isoprenoid moiety and...

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Detalles Bibliográficos
Autores principales: Berg, Tracy J., Gastonguay, Adam J., Lorimer, Ellen L., Kuhnmuench, John R., Li, Rongshan, Fields, Alan P., Williams, Carol L.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975149/
https://www.ncbi.nlm.nih.gov/pubmed/20709748
http://dx.doi.org/10.1074/jbc.M110.129916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975149/
https://www.ncbi.nlm.nih.gov/pubmed/20709748
http://dx.doi.org/10.1074/jbc.M110.129916

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