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Prognostic significance of p53-expression in colorectal carcinoma as measured by a luminometric immunoassay

Background: Mutations of the TP53 gene induce the production of abnormal p53-protein with a prolonged half-life allowing its detection by monoclonal antibodies. In the following study we examined if elevated levels of p53 correlate with worse prognosis in colorectal cancer. Methods: We have quantifi...

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Detalles Bibliográficos
Autores principales: Lotter, Oliver, Amr, Amro, Safi, Farouk
Formato: Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975257/
https://www.ncbi.nlm.nih.gov/pubmed/21063465
http://dx.doi.org/10.3205/000113