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Inhibition of Glioblastoma Growth by the Thiadiazolidinone Compound TDZD-8

BACKGROUND: Thiadiazolidinones (TDZD) are small heterocyclic compounds first described as non-ATP competitive inhibitors of glycogen synthase kinase 3β (GSK-3β). In this study, we analyzed the effects of 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8), on murine GL261 cells growth in vitr...

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Detalles Bibliográficos
Autores principales: Aguilar-Morante, Diana, Morales-Garcia, Jose Angel, Sanz-SanCristobal, Marina, Garcia-Cabezas, Miguel Angel, Santos, Angel, Perez-Castillo, Ana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975629/
https://www.ncbi.nlm.nih.gov/pubmed/21079728
http://dx.doi.org/10.1371/journal.pone.0013879