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Distinct Signature of Altered Homeostasis in Aging Rod Photoreceptors: Implications for Retinal Diseases

BACKGROUND: Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading cause of visual impairment and blindness in the elderly. Rod photoreceptors are especially vulnerable to genetic defects and change...

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Detalles Bibliográficos
Autores principales: Parapuram, Sunil K., Cojocaru, Radu I., Chang, Jessica R., Khanna, Ritu, Brooks, Matthew, Othman, Mohammad, Zareparsi, Sepideh, Khan, Naheed W., Gotoh, Norimoto, Cogliati, Tiziana, Swaroop, Anand
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975639/
https://www.ncbi.nlm.nih.gov/pubmed/21079736
http://dx.doi.org/10.1371/journal.pone.0013885