Cargando…

Distinct Signature of Altered Homeostasis in Aging Rod Photoreceptors: Implications for Retinal Diseases

BACKGROUND: Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading cause of visual impairment and blindness in the elderly. Rod photoreceptors are especially vulnerable to genetic defects and change...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parapuram, Sunil K., Cojocaru, Radu I., Chang, Jessica R., Khanna, Ritu, Brooks, Matthew, Othman, Mohammad, Zareparsi, Sepideh, Khan, Naheed W., Gotoh, Norimoto, Cogliati, Tiziana, Swaroop, Anand
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975639/ https://www.ncbi.nlm.nih.gov/pubmed/21079736 http://dx.doi.org/10.1371/journal.pone.0013885

Ejemplares similares

Divergent Effects of HSP70 Overexpression in Photoreceptors During Inherited Retinal Degeneration
por: Jiang, Ke, et al.
Publicado: (2020)

Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by In Vivo NRL Targetome Analysis
por: Hao, Hong, et al.
Publicado: (2012)

Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal
por: Kelley, Ryan A., et al.
Publicado: (2020)

Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL
por: Zelinger, Lina, et al.
Publicado: (2017)

Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation
por: Campla, Christie K., et al.
Publicado: (2017)

Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation
por: Chen, Holly Yu, et al.
Publicado: (2016)

Protective Gene Expression Changes Elicited by an Inherited Defect in Photoreceptor Structure
por: Sharma, Yagya V., et al.
Publicado: (2012)

Characterization of the retinal proteome during rod photoreceptor genesis
por: Barnhill, Alison E, et al.
Publicado: (2010)

A role for prenylated rab acceptor 1 in vertebrate photoreceptor development
por: Dickison, Virginia M, et al.
Publicado: (2012)

Physiological and Microfluorometric Studies of Reduction and Clearance of Retinal in Bleached Rod Photoreceptors
por: Tsina, Efthymia, et al.
Publicado: (2004)

Inverse pattern of photoreceptor abnormalities in retinitis pigmentosa and cone–rod dystrophy
por: Yokochi, Midori, et al.
Publicado: (2012)

Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa
por: Vargas, Andrew, et al.
Publicado: (2017)

Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration
por: Murga-Zamalloa, Carlos A., et al.
Publicado: (2010)

Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity
por: Kubo, Shun, et al.
Publicado: (2021)

Vigabatrin-Induced Retinal Toxicity Is Partially Mediated by Signaling in Rod and Cone Photoreceptors
por: Yang, Jin, et al.
Publicado: (2012)

Potential of Small Molecule–Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa
por: Nakamura, Paul A., et al.
Publicado: (2016)

Differences in calcium homeostasis between retinal rod and cone photoreceptors revealed by the effects of voltage on the cGMP-gated conductance in intact cells
Publicado: (1994)

Transcriptome Dynamics of Developing Photoreceptors in Three‐Dimensional Retina Cultures Recapitulates Temporal Sequence of Human Cone and Rod Differentiation Revealing Cell Surface Markers and Gene Networks
por: Kaewkhaw, Rossukon, et al.
Publicado: (2015)

Clarifying the composition of the ATP consumption factors required for maintaining ion homeostasis in mouse rod photoreceptors
por: Muangkram, Yuttamol, et al.
Publicado: (2023)

A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors
por: Santhanam, Abirami, et al.
Publicado: (2020)

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity
por: Alves, C. Henrique, et al.
Publicado: (2019)

Functional Optical Coherence Tomography Enables In Vivo Physiological Assessment of Retinal Rod and Cone Photoreceptors
por: Zhang, Qiuxiang, et al.
Publicado: (2015)

Dendritic stratification differs among retinal OFF bipolar cell types in the absence of rod photoreceptors
por: Puller, Christian, et al.
Publicado: (2017)

Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction
por: Wiemann, Susanne, et al.
Publicado: (2021)

Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment
por: Ross, Bing X., et al.
Publicado: (2020)

Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition
por: Rao, Kollu N., et al.
Publicado: (2015)

REEP6 mediates trafficking of a subset of Clathrin-coated vesicles and is critical for rod photoreceptor function and survival
por: Veleri, Shobi, et al.
Publicado: (2017)

Low-Level Gestational Lead Exposure Increases Retinal Progenitor Cell Proliferation and Rod Photoreceptor and Bipolar Cell Neurogenesis in Mice
por: Giddabasappa, Anand, et al.
Publicado: (2011)

THE ULTRASTRUCTURE OF LIPID-DEPLETED ROD PHOTORECEPTOR MEMBRANES
por: Nir, Izhak, et al.
Publicado: (1974)

Ionizable groups and conductances of the rod photoreceptor membrane
por: Pinto, LH, et al.
Publicado: (1978)

Resonance Raman microscopy of rod and cone photoreceptors
Publicado: (1982)

Transduction Gain in Light Adaptation of Rod Photoreceptors
por: Pepperberg, David R.
Publicado: (2001)

Transcripts within rod photoreceptors of the Zebrafish retina
por: Sun, Chi, et al.
Publicado: (2018)

Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina
por: Campla, Christie K., et al.
Publicado: (2022)

Rod Bipolar Cells Require Horizontal Cells for Invagination Into the Terminals of Rod Photoreceptors
por: Nemitz, Lena, et al.
Publicado: (2019)

HIPRO: A High-Efficiency, Hypoxia-Induced Protocol for Generation of Photoreceptors in Retinal Organoids from Mouse Pluripotent Stem Cells
por: Chen, Holly Y., et al.
Publicado: (2020)

Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system
por: Bhatt, Lavinia, et al.
Publicado: (2010)

Non-canonical regulation of phosphatidylinositol 3-kinase gamma isoform activity in retinal rod photoreceptor cells
por: Gupta, Vivek K, et al.
Publicado: (2015)

Fasudil, a Clinically Used ROCK Inhibitor, Stabilizes Rod Photoreceptor Synapses after Retinal Detachment
por: Townes-Anderson, Ellen, et al.
Publicado: (2017)

Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodeling
por: Zhang, Rui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rtlm3jbi6jq8hrmek6d7f4dn1f