Use of N-Methylformamide as a Solvent in Indium-Promoted Barbier Reactions en Route to Enediyne and Epoxy Diyne Formation: Comparison of Rate and Stereoselectivity in C−C Bond-Forming Reactions with Water

[Image: see text] Indium-promoted coupling reactions between propargyl aldehydes (1) and α-chloropropargylphenyl sulfide are reported. Although water has been shown to accelerate indium metal promoted reactions, the reverse pattern was observed in this series. Use of N-methylformamide (NMF), which h...

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Detalles Bibliográficos
Autores principales: Frimpong, Kwame, Wzorek, Joseph, Lawlor, Claire, Spencer, Katharine, Mitzel, Thomas
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976581/
https://www.ncbi.nlm.nih.gov/pubmed/19634900
http://dx.doi.org/10.1021/jo900763u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976581/
https://www.ncbi.nlm.nih.gov/pubmed/19634900
http://dx.doi.org/10.1021/jo900763u

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